研究業績

論文

論文 2011年－2024年

• Y. Yokoyama, S. Ariyasu, M. Karasawa, C. Kasai, Y. Aiba, H. Sugimoto, O. Shoji, "Bacterial acyl homoserine lactones triggered non-native substrate hydroxylation catalysed by directed-evolution-derived cytochrome P450BM3 mutants" , ChemCatChem, 16, (2024) e202401641

   https://doi.org/10.1002/cctc.202401641

  
            
• H. Inaba, Y. Shisaka, S. Ariyasu, E. Sakakibara, G. Ueda, Y. Aiba, N. Shimizu, H. Sugimoto, O. Shoji, "Heme-Substituted Protein Assembly Bridged by Synthetic Porphyrin: Achieving Controlled Configuration while Maintaining Rotational Freedom" , RSC Adv., 14, (2024) 8829-8836

   https://doi.org/10.1039/D4RA01042F

  
            
• Y. Lee, B. Kim, S. Kim, E. W. H. Ng, S. Ariyasu, O. Shoji, S. Yoon, H. Hirao, J. Cho, "Influenceof Solventson CatalyticC−H BondOxidationby aCopper(II)−AlkylperoxoComplex" , ACS Catal., 14, (2024) 3524-3532

   https://doi.org/10.1021/acscatal.3c05643

  
            
• Y. Kodama, S. Ariyasu, M. Karasawa, Y. Aiba, O. Shoji, "Highly Selective Hydroxylation of Gaseous Alkanes at the Terminal Position by Wild-type CYP153A33" , Catal. Sci. Technol., 13, (2023) 6146-6152

   https://doi.org/10.1039/D3CY00752A

  
            
• S. Ariyasu, K. Yonemura, C. Kasai, Y. Aiba, H. Onoda, Y. Shisaka, H. Sugimoto, T. Tosha, M. Kubo, T. Kamachi, K. Yoshizawa, O. Shoji, "Catalytic Oxidation of Methane by Wild-Type Cytochrome P450BM3 with Chemically Evolved Decoy Molecules" , ACS Catal., 13, (2023) 8613-8623

   https://doi.org/10.1021/acscatal.3c01158

  
            
• J. K. Stanfield, H. Onoda, S. Ariyasu, C. Kasai, E. M. Burfoot, H. Sugimoto, O. Shoji "Investigating the applicability of the CYP102A1-decoy-molecule system to other members of the CYP102A subfamily" , J. Inorg. Biochem., 245, (2023) 112235

   https://doi.org/10.1016/j.jinorgbio.2023.112235

  
            
• K. Suzuki, J. K. Stanfield, K. Omura, Y. Shisaka, S. Ariyasu, C. Kasai, Y. Aiba, H. Sugimoto, O. Shoji "A Compound I Mimic Reveals the Transient Active Species of a Cytochrome P450 Enzyme: Insight into the Stereoselectivity of P450-Catalysed Oxidations" , Angew. Chem. Int. Ed., 62, (2023) e202215706

   https://doi.org/10.1002/anie.202215706

  
            
• Y. Shisaka, O. Shoji "Bridging the gap: Unveiling novel functions of a bacterial haem-acquisition protein capturing diverse synthetic porphyrinoids" , Coord. Chem. Res., 472, (2022) 214793.

   https://doi.org/10.1016/j.ccr.2022.214793

  
            
• K. Omura, Y. Aiba, K. Suzuki, S. Ariyasu, H. Sugimoto, O. Shoji "A P450 Harboring Manganese Protoporphyrin IX Generates a Manganese Analogue of Compound I by Activating Dioxygen" , ACS Catal., 12, (2022) 11108-11117.

   https://doi.org/10.1021/acscatal.2c01345

  
            
• Y. Aiba, M. Shibata, O. Shoji "Sequence-Specific Recognition of Double-Stranded DNA by Peptide Nucleic Acid Forming Double-Duplex Invasion Complex" , Appl. Sci., 12, (2022) 3677.

   https://doi.org/10.3390/app12073677

  
            
• Y. Shisaka, E. Sakakibara, K. Suzuki, J. K. Stanfield, H. Onoda, G. Ueda, M. Hatano, H. Sugimoto, O. Shoji "Tetraphenylporphyrin Enters the Ring: First Example of a Complex Between Highly Bulky Porphyrins and a Protein" , ChemBioChem, 23, (2022) e202200095

  https://doi.org/10.1002/cbic.202200095

  
            
• A. Takiguchi, E. Sakakibara, H. Sugimoto, O. Shoji, H. Shinokubo "A Heme-Acquisition Protein Reconstructed with a Cobalt 5-Oxaporphyrinium Cation and Its Growth-Inhibition Activity Toward Multidrug-Resistant Pseudomonas aeruginosa" , Angew. Chem. Int. Ed., 61, (2022) e202112456 Angew. Chem., 134, (2022) e202112456.

  https://doi.org/10.1002/anie.202112456

  https://doi.org/10.1002/ange.202112456

  
            
• M. Karasawa, K. Yonemura, J. K. Stanfield, K. Suzuki, O. Shoji "Designer Outer Membrane Protein Facilitates Uptake of Decoy Molecules into a Cytochrome P450BM3-Based Whole-Cell Biocatalyst (English ver.)" "Ein Designeraußenmembranprotein fördert die Aufnahme von Täuschmolekülen in einen auf Zytochrom P450BM3 beruhenden Ganzzellbiokatalysator (German ver.)" , Angew. Chem. Int. Ed., 61, (2022) e202111612. Angew. Chem., 134, (2022) e202111612.

  https://doi.org/10.1002/anie.202111612

  https://doi.org/10.1002/ange.202111612

  
            
• J. K. Stanfield, O. Shoji "The Power of Deception: Using Decoy Molecules to Manipulate P450BM3 Biotransformations" , Chem. Lett., 50, (2021) 2025-2031

  https://doi.org/10.1246/cl.210584

  
            
• H. Onoda, S. Tanaka, Y. Watanabe, O. Shoji "Exploring Hitherto Uninvestigated Reactions of the Fatty Acid Peroxygenase CYP152A1: Catalase Reaction and Compound I Formation" , Faraday Discussions,234, (2022) 304-314

  https://doi.org/10.1039/D1FD00065A

  
            
• H. Nanaura, H. Kawamukai, A. Fujiwara, T. Uehara, Y. Aiba, M. Nakanishi, T. Shiota, M. Hibino, P. Wiriyasermku, S. Kikuchi, R. Nagata, M. Matsubayashi, Y. Shinkai, T. Niwa, T. Mannen, N. Morikawa, N. Iguchi, T. Kiriyama, K. Morishima, R. Inoue, M. Sugiyama, T. Oda, N. Kodera, S. Toma-Fukai, M. Sato, H. Taguchi, S. Nagamori, O. Shoji, K. Ishimori, H. Matsumura, K. Sugie, T. Saio, T. Yoshizawa, E. Mori "C9orf72-derived arginine-rich poly-dipeptides impede phase modifiers" , Nat. Commun., 12, (2021) 5301.

  https://doi.org/10.1038/s41467-021-25560-0

  
            
• T. Nomura, T. Kimura, Y. Kanematsu, D. Yamada, K. Yamashita, K. Hirata, G. Ueno, H. Murakami, T. Hisano, R. Yamagiwa, H. Takeda, C. Gopalasingam, R. Kousaka, S. Yanagisawa, O. Shoji, T. Kumasaka, M. Yamamoto, Y. Takano, H. Sugimoto, T. Tosha, M. Kubo, Y. Shiro "Short-lived intermediate in N2O generation by P450 NO reductase captured by time-resolved IR spectroscopy and XFEL crystallography" , Proc. Natl. Acad. Sci. USA, 118, (2021) e210148118.

  https://doi.org/10.1073/pnas.2101481118

  
            
• J. K. Stanfield, K. Suzuki, K. Yonemura, T. Malewschik, O. Shoji "ENGANANDO O CITOCROMO P450BM3: CATÁLISE DE VÁRIAS TRANSFORMAÇÕES DE SUBSTRATOS NÃO NATIVOS USANDO MOLÉCULAS-TRAIÇOEIRAS" , Quim. Nova, 44, (2021) 982-998.

  http://dx.doi.org/10.21577/0100-4042.20170747

  
            
• Y. Aiba, G. Urbina, M. Shibata, O. Shoji "Investigation of the Characteristics of NLS-PNA: Influence of NLS Location on Invasion Efficiency" , Appl. Sci., 10, (2020) 8663.

  https://doi.org/10.3390/app10238663

  
            
• T. Nishimura, T. Ikeue, O. Shoji, H. Shinokubo, Y. Miyake "Iron(III) 5,15-Diazaporphyrin Catalysts for the Direct Oxidation of C(sp³)−H Bonds" , Inorg. Chem., 59, (2020) 15751.

  https://dx.doi.org/10.1021/acs.inorgchem.0c02166

  
            
• K. Suzuki, Y. Shisaka, J. K. Stanfield, Y. Watanabe, O. Shoji "Enhanced cis- and enantioselective cyclopropanation of styrene catalysed by cytochrome P450BM3 using decoy molecules" , Chem. Commun., 56, (2020) 11026－11029.

  https://doi.org/ 10.1039/d0cc04883f

  
            
• K. Yonemura, S. Ariyasu, J. K. Stanfield, K. Suzuki, H. Onoda, C. Kasai, H. Sugimoto, Y. Aiba, Y. Watanabe, O. Shoji "Systematic Evolution of Decoy Molecules for the Highly Efficient Hydroxylation of Benzene and Small Alkanes Catalyzed by Wild-Type Cytochrome P450BM3" , ACS Catal., 10, (2020) 9136－9144

  https://doi.org/10.1021/acscatal.0c01951

  
            
• S. Ariyasu, J. K. Stanfield, Y. Aiba, O. Shoji "Expanding the Applicability of Cytochrome P450s and other Haemoproteins" , Curr. Opin, Chem. Biol., 59,(2020) 155-163

  https://doi.org/10.1016/j.cbpa.2020.06.010

  
            
• Y. Kobayashi, K. Kohara, Y. Kiuchi, H. Onoda, O. Shoji, H. Yamaguchi "Control of microenvironment around enzymes by hydrogels" , Chem. Commun., 56,(2020) 6723-6726

  https://doi.org/10.1039/D0CC01332C

  
            
• J. K. Stanfield, K. Omura, A. Matsumoto, C. Kasai, H. Sugimoto, Y. Shiro, Y. Watanabe, O. Shoji "Crystals in Minutes: Instant On-Site Microcrystallisation of Various Flavours of the CYP102A1 (P450BM3) Haem Domain" , Angew. Chem. Int. Ed., 59, 7611-7618 (2020), Angew. Chem., 132, 7681-7689 (2020)

  https://doi.org/10.1002/anie.201913407

  https://doi.org/10.1002/ange.201913407

  
            
• M. Hibino, Y. Aiba, O. Shoji, "Cationic Guanine: Positively Charged Nucleobase with Improved DNA Affinity Inhibits Self-Duplex Formation" , Chem. Commun., 56, 2546-2549 (2020)

  https://doi.org/10.1039/D0CC00169D

  
            
• Y. Watanabe, Y. Aiba, S. Ariyasu, S. Abe, "Molecular Design and Regulation of Metalloenzyme Activities through two Novel Approaches: Ferritin and P450s" , Bull. Chem. Soc. Jpn. (Award Accounts), 93, 379-392 (2020).

  https://doi.org/10.1246/bcsj.20190305

  
            
• S. Ariyasu, Y. Kodama(equal contribution), C. Kasai, Z. Cong, J. K. Stanfield, Y. Aiba, Y. Watanabe, O. Shoji, "Development of a High-Pressure Reactor Based on Liquid-Flow Pressurisation to Facilitate Enzymatic Hydroxylation of Gaseous Alkanes" , ChemCatChem, 11,4709-4714(2019).

  https://doi.org/10.1002/cctc.201901323

  
            
• Y. Shisaka, Y. Iwai, S. Yamada, H. Uehara, T. Tosha, H. Sugimoto, Y. Shiro, J. K. Stanfield, K. Ogawa, Y. Watanabe, O. Shoji, "Hijacking the Heme Acquisition System of Pseudomonas aeruginosa for the Delivery of Phthalocyanine as an Antimicrobial" , ACS Chemical Biology, 14,1637-1642(2019).

  https://doi.org/10.1021/acschembio.9b00373

  
            
• E. Sakakibara, Y. Shisaka, H. Onoda, D. Koga, N. Xu, T. Ono, Y. Hisaeda, H. Sugimoto, Y. Shiro, Y. Watanabe, O. Shoji, "Highly malleable haem-binding site of the haemoprotein HasA permits stable accommodation of bulky tetraphenylporphycenes" , RSC Advances, 9,18697-18702(2019).

  https://doi.org/10.1039/C9RA02872B

  
            
• S. Dezvarei, O. Shoji, Y. Watanabe, S. G. Bell "The effect of decoy molecules on the activity of the P450BM3 holoenzyme and a heme domain peroxygenase variant" , Catalysis Communications, 124,97-102(2019).

   

• O. Shoji, Y. Aiba, Y. Watanabe "Hoodwinking Cytochrome P450BM3 into Hydroxylatiing Non-Native Substrates by Exploiting Its Substrate Misrecognition" , Acc. Chem. Res., 52, 4, 925-934(2019).

  doi: 10.1021/acs.accounts.8b00651

• E. Goto, Y. Haga, M. Kubo, T. Itoh, C. Kasai, O. Shoji, K. Yamamoto, C. Matsumura, T. Nakano, H. Inui "Metabolic enhancement of 2,3´,4,4´,5-pentachlorobiphenyl (CB118) using cytochrome P450 monooxygenase isolated from soil bacterium under the presence of perfluorocarboxylic acids (PFCAs) and the structural basis of its metabolism" , Chemosphere, 210, 376-383(2018).

  doi: 10.1016/j.chemosphere.2018.07.026.

• M. Hibino, Y. Aiba, Y. Watanabe, O. Shoji "Peptide Nucleic Acid Conjugated with Ru‐complex Stabilizing Double‐Duplex Invasion Complex Even under Physiological Conditions" , ChemBioChem, 19, 1601-1604(2018).

  https://doi.org/10.1002/cbic.201800256

  
            
• M. Karasawa, J. K. Stanfield, S. Yanagisawa, O. Shoji, Y. Watanabe  "Whole-Cell Biotransformation of Benzene to Phenol Catalysed by Intracellular Cytochrome P450BM3 Activated by External Additives" , Angew. Chem. Int. Ed., 57, 12264-12269(2018). , Angew. Chem., 130, 12444-12449(2018).  https://doi.org/10.1002/ange.201804924(Germany ver.)  https://doi.org/10.1002/anie.201804924(English ver.)
            
• K. Omura, Y. Aiba, H. Onoda, J. K. Stanfield, S. Ariyasu, H. Sugimoto, Y. Shiro, O. Shoji, Y. Watanabe,"Reconstitution of Full-Length P450BM3 with an Artificial Metal Complex by Utilising the Transpeptidase Sortase A" , Chem. Commun., 54, 7892-7895(2018)
  10.1039/C8CC02760A
            
• N. Ma, Z. Chen, J. Chen, J. Chen, C. Wang, H. Zhou, L. Yao, O. Shoji, Y. Watanabe, Z. Cong ,"Dual‐Functional Small Molecules for Generating an Efficient Cytochrome P450BM3 Peroxygenase" , Angew. Chem. Int. Ed., 57, 7628-7633(2018)
  DOI:10.1002/anie.201801592
            
• S. Dezvarei, H. Onoda, O. Shoji, Y. Watanabe, S. G. Bell , "Efficient hydroxylation of cycloalkanes by co-addition of decoy molecules to variants of the cytochrome P450 CYP102A1", J. Inorg. Biochem., 137-145(2018)
  https://doi.org/10.1016/j.jinorgbio.2018.03.001
            
• H. Onoda, O. Shoji, K. Suzuki, H. Sugimoto, Y. Shiro, Y. Watanabe , " α-Oxidative Decarboxylation of Fatty Acids Catalysed by Cytochrome P450 Peroxygenases Yielding Shorter-Alkyl-Chain Fatty Acids", Catalysis Science & Technology, 8, 434-442 (2018).
  http://dx.doi.org/10.1039/C7CY02263H
  
            
• T. Tosha, T. Nomura, T. Nishida, N. Saeki, K. Okubayashi, R. Yamagiwa, M. Sugahara, T. Nakane, K. Yamashita, K. Hirata, G. Ueno, T. Kimura, T. Hisano, K. Muramoto, H. Sawai, H. Takeda, E. Mizohata, A. Yamashita, Y. Kanematsu, Y. Takano, E. Nango, R. Tanaka, O. Nureki, O. Shoji, Y. Ikemoto, H. Murakami, S. Owada, K. Tono, M. Yabashi, M. Yamamoto, H. Ago, S. Iwata, H. Sugimoto, Y. Shiro, M. Kubo; , " Capturing an Initial Intermediate during the P450nor Enzymatic Reaction using Time-Resolved XFEL Crystallography and Caged-Substrate", Nature Communiactions, 8, 1585 (2017).
            
• K. Yamamoto, M. Oyaizu, T. Takahashi, Y. Watanabe, O. Shoji, " Inhibiting Aggregation of Beta-Amyloid by Folded and Unfolded Forms of Fimbrial Protein of Gram-Negative Bacteria", ChemistrySelect, 2, 9058-9062 (2017).
  http://dx.doi.org/10.1002/slct.201700658
            
• H. Uehara, Y. Shisaka, T. Nishimura, H. Sugimoto, Y. Shiro, Y. Miyake, H. Shinokubo, Y. Watanabe, O. Shoji, " Structures of the Heme Acquisition Protein HasA with Iron(III)-5,15-Diphenylporphyrin and Derivatives Thereof as an Artificial Prosthetic Group", Angew. Chem. Int. Ed., 56, 15279-15283 (2017).
  http://dx.doi.org/10.1002/anie.201707212
            
• K. Suzuki, J. K. Stanfield, O. Shoji, S. Yanagisawa, H. Sugimoto, Y. Shiro, Y. Watanabe , " Control of Stereoselectivity of Benzylic Hydroxylation Catalysed by Wild-type Cytochrome P450BM3 Using Decoy Molecules", Catal. Sci. Technol., 7, 3332-3338 (2017).
  http://dx.doi.org/10.1039/C7CY01130J
            
• O. Shoji, S.Yanagisawa, J. Kyle Stanfield, K. Suzuki, Z. Cong, H. Sugimoto, Y. Shiro, Y. Watanabe , " Direct Hydroxylation of Benzene to Phenol by Cytochrome P450BM3 Triggered by Amino Acid Derivatives ", Angew. Chem. Int. Ed., 56, 10324-10329 (2017). The frontispiece picture of issue 35.
  http://dx.doi.org/10.1002/anie.201703461
         
• O. Shoji, Y. Watanabe, "Monooxygenation of Nonnative Substrates Catalyzed by Bacterial Cytochrome P450s Facilitated by Decoy Molecules ", Chemistry Letters, 46, 278-288 (2017).The Front cover of the issue 3.
  http://dx.doi.org/10.1246/cl.160963
  
• S.C. Chien, O. Shoji, Y. Morimoto, Y. Watanabe, "Use of apomyoglobin to gently remove heme from a H₂O₂-dependent cytochrome P450 and allow its reconstitution ", New J. Chem., 41, 302-307 (2017).
  http://dx.doi.org/10.1039/C6NJ02882A
                     
• O. Shoji, T. Fujishiro, K. Nishio, Y. Kano, H. Kimoto, S. Chien, H. Onoda, A. Muramatsu, S. Tanaka, A. Hori, H. Sugimoto, Y. Shiro and Y. Watanabe, "A Substrate-Binding-State Mimic of H2O2-Dependent Cytochrome P450 Produced by One-point Mutagenesis and Peroxygenation of Non-native Substrates ", Catal. Sci. Tech. 6, 5806-5811 (2016). The Front cover of the issue 15.
  http://dx.doi.org/10.1039/C6CY00630B
                     
• S. D. Munday, O. Shoji, Y. Watanabe, L. L. Wong, S. G. Bell, "Improved oxidation of aromatic and aliphatic hydrocarbons using rate enhancing variants of P450Bm3 in combination with decoy molecules ", Chem. Commun., 52, 1036-1039 (2016).
  http://dx.doi.org/10.1039/C5CC09247G
                     
• H. Onoda, O. Shoji, Y. Watanabe, "Acetate anion-triggered peroxygenation of non-native substrates by wild-type cytochrome P450s", Dalton Trans, 44, 15316-15323 (2015).
  http://dx.doi.org/10.1039/C5DT00797F
     
• N. Kawakami, Z. Cong, O. Shoji, Y. Watanabe, "Highly efficient hydroxylation of gaseous alkanes at reduced temperature catalyzed by cytochrome P450BM3 assisted by decoy molecules", Journal of Porphyrins and Phthalocyanines, 19, 329-334 (2015).
  http://dx.doi.org/10.1142/S1088424615500145                  
• Z. Cong, O. Shoji, C. Kasai, N. Kawakami, H. Sugimoto, Y. Shiro, Y. Watanabe, "Activation of Wild-type Cytochrome P450BM3 by the Next Generation of Decoy Molecules: Enhanced Hydroxylation of Gaseous Alkanes and Crystallographic Evidence", ACS Catalysis, 5,  150–156 (2015).
  http://dx.doi.org/10.1021/cs501592f
                     
• O. Shoji, Y. Watanabe, "Bringing out the potential of wild-type cytochrome P450s using decoy molecules: Oxygenation of nonnative substrates by bacterial cytochrome P450s " Isr. J. Chem., 55 (1), 32–39 (2015).
  http://dx.doi.org/10.1002/ijch.201400096
                     
• O. Shoji, Y. Watanabe, "Peroxygenase reactions catalyzed by cytochromes P450" , J. Biol. Inorg. Chem., 19, 529-539 (2014).
  http://dx.doi.org/10.1007/s00775-014-1106-9
                     
• A. Benner, A. Bonifazi, C. Shirataki, L. Temme, D. Schepmann, W. Quaglia, O. Shoji, Y. Watanabe, C. Daniliuc, B. Wünsch, "GluN2B-Selective N-Methyl-d-aspartate (NMDA) Receptor Antagonists Derived from 3-Benzazepines: Synthesis and Pharmacological Evaluation of Benzo[7]annulen-7-amines" , ChemMedChem, 9, 741–751 (2014).
  http://dx.doi.org/10.1002/cmdc.201300547
                     
• C. Shirataki, O. Shoji, M. Terada, S. Ozaki, H. Sugimoto, Y. Shiro, Y. Watanabe, "Inhibition of Heme Uptake in Pseudomonas aeruginosa by its Hemophore (HasAp) Bound to Synthetic Metal Complexes" , Angew. Chem. Int. Ed., 53, 2862–2866 (2014). The inside cover of the issue 11.
  http://dx.doi.org/10.1002/anie.201307889
                     
• R. Nishimura, T. Shibata, I. Ishigami, T. Ogura, H. Tai, S. Nagao, T. Matsuo, S Hirota, O. Shoji, Y. Watanabe, K. Imai, S. Neya, A. Suzuki, Y. Yamamoto, "Electronic Control of Discrimination between O2 and CO in Myoglobin Lacking the Distal Histidine Residue" , Inorg. Chem., 53, 1091–1099 (2013).
  http://dx.doi.org/ 10.1021/ic402625s
                      
• O. Shoji, T. Kunimatsu, N. Kawakami, Y. Watanabe, "Highly Selective Hydroxylation of Benzene to Phenol by Wild-type Cytochrome P450BM3 Assisted by Decoy Molecules" ,Angew. Chem. Int. Ed. 52, 6606-6610 (2013). The frontispiece picture of issue 26.
  http://dx.doi.org/10.1002/anie.201300282
                      
• N. Kawakami, O. Shoji, Y. Watanabe, "Direct hydroxylation of primary carbons in small alkanes by wild-type cytochrome P450BM3 containing perfluorocarboxylic acids as decoy molecules" ,Chem. Sci. 4, 2344-2348 (2013). The back cover of issue 6.
  http://dx.doi.org/10.1039/C3SC50378J
                     
• N. Kawakami, O. Shoji, Y. Watanabe, "Single-step reconstitution of apo-hemoproteins at the disruption stage of Escherichia coli cells" ,ChemBioChem13, 2045-2047 (2012).The back cover of issue 14.
  http://dx.doi.org/10.1002/cbic.201200446
  
• T. Fujishiro, O. Shoji, N. Kawakami, T. Watanabe, H. Sugimoto, Y. Shiro, Y. Watanabe, "Chiral-Substrate-Assisted Stereoselective Epoxidation Catalyzed by H2O2-Dependent Cytochrome P450SPα ",Chem. Asian J.7, 2286-2293(2012). The front cover of the issue 10. Selected as the subject of an upcoming press release.Highlighted on ChemistryViews.
  http://dx.doi.org/10.1002/asia.201200250
  
• J. Xu, O. Shoji,T. Fujishiro, T. Ohki, T. Ueno, Y. Watanabe, "Construction of biocatalysts using the myoglobin scaffold for the synthesis of indigo from indole" ,Catalysis Science & Technology.2,739-744 (2012).The front cover of the issue 4.
  http://dx.doi.org/10.1039/c2cy00427e
  
• T. Fujishiro, O. Shoji, S. Nagano, H. Sugimoto, Y. Shiro, Y. Watanabe, "Crystal structure of H2O2-dependent cytochrome P450SPα with its bound fatty acid substrate: insight into the regioselective hydroxylation of fatty acids at the α position" ,J. Biol. Chem. 286, 29941-29950 (2011).
  http://dx.doi:10.1074/jbc.M111.245225
  
• N. Kawakami, O. Shoji, Y. Watanabe, "Use of Perfluorocarboxylic Acids To Trick Cytochrome P450BM3 into Initiating the Hydroxylation of Gaseous Alkanes",Angew. Chem. Int. Ed. 50, 5315-5318(2011).
  http://dx.doi.org/10.1002/anie.201007975
  
• O. Shoji, Y. Watanabe, "Design of H2O2-Dependent Oxidation Catalyzed by Hemoproteins" ,Metallomics 3, 379-388 (2011).
  http://dx.doi.org/10.1039/c0mt00090f
  
• H. Nakajima, O. Shoji, Y. Watanabe, "Molecular design of heme proteins for future application" ,Catalysis Surveys from Asia15, 134-143(2011).
  http://dx.doi.org/10.1007/s10563-011-9117-9
• T. Fujishiro, O. Shoji, Y. Watanabe, "Non-covalent modification of the active site of cytochrome P450 for inverting the stereoselectivity of monooxygenation",Tetrahedron Lett. 52 395-397 (2011).
  http://dx.doi.org/10.1016/j.tetlet.2010.11.048